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BIRC2

Official Full Name
baculoviral IAP repeat containing 2
Organism
Homo sapiens
GeneID
329
Background
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Synonyms
API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1;

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