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Bcl11b

Official Full Name
B-cell CLL/lymphoma 11B (zinc finger protein)
Background
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Synonyms
BCL11B; B-cell CLL/lymphoma 11B (zinc finger protein); ATL1; RIT1; CTIP2; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha; B-cell lymphoma/leukemia 11B; hRit1; BCL-11B; BCL11B/TRDC fusion; B-cell lymphoma/leukaemia 11B; COUP-TF-interacting protein 2; zinc finger protein hRit1 alpha; radiation-induced tumor suppressor gene 1 protein; B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein

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