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BMPR1B


Official Full Name
bone morphogenetic protein receptor type 1B
Organism
Homo sapiens
Gene ID
658
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Synonyms
ALK6; AMD3; AMDD; BDA2; ALK-6; BDA1D; CDw293

Cat.No. Product Name Price
CLOE-1395 Human BMPR1B Insect Cell Lysate Inquiry
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SHG054055 shRNA set against Mouse Bmpr1b(NM_007560.3) Inquiry
SHG102475 shRNA set against Rat Bmpr1b(NM_001024259.1) Inquiry
SHH247170 shRNA set against Mouse BMPR1B (NM_007560.3) Inquiry
SHH247174 shRNA set against Rat BMPR1B (NM_001024259.1) Inquiry
SHW005632 shRNA set against Chicken BMPR1B (NM_205132) Inquiry
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CDCB167107 Chicken BMPR1B ORF Clone (NM_205132) Inquiry
CDFG021931 Mouse Bmpr1b cDNA Clone(BC065143) Inquiry
CDFR003532 Rat Bmpr1b cDNA Clone(NM_001024259.1) Inquiry
MiUTR1M-02235 BMPR1B miRNA 3'UTR clone Inquiry
MiUTR1R-00586 BMPR1B miRNA 3'UTR clone Inquiry
CDCB187114 Rabbit BMPR1B ORF clone (XM_008267582.1) Inquiry
CDCL182899 Mouse BMPR1B ORF clone(NM_007560.3) Inquiry
CDCL182900 Rat BMPR1B ORF clone(NM_001024259.1) Inquiry
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