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BMP6


Official Full Name
bone morphogenetic protein 6
Organism
Homo sapiens
Gene ID
654
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
Synonyms
IO; VGR; VGR1

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SHG102151 shRNA set against Human BMP6(NM_001718.4) Inquiry
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CDFR010908 Rat Bmp6 cDNA Clone(NM_013107.1) Inquiry
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MiUTR1M-02230 BMP6 miRNA 3'UTR clone Inquiry
MiUTR1R-00584 BMP6 miRNA 3'UTR clone Inquiry
CDCB169486 Danio rerio BMP6 ORF Clone (NM_001013339) Inquiry
CDCB184971 Rabbit BMP6 ORF clone (XM_008262354.1) Inquiry
CDCR034856 Mouse Bmp6 ORF clone (NM_007556.2) Inquiry
CDCR377855 Rat Bmp6 ORF Clone(NM_013107.1) Inquiry
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