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bmp2b

Official Full Name
bone morphogenetic protein 2b
Organism
Danio rerio
GeneID
30632
Background
Enables identical protein binding activity and protein heterodimerization activity. Involved in dorsal/ventral axis specification. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and regionalization. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; digestive system; ectoderm; fin; and mesoderm. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); hemochromatosis type 1; otosclerosis; short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1; and tooth agenesis. Orthologous to human BMP2 (bone morphogenetic protein 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
swr; bmp2; bmp-2; cb670; zbmp2; bmp2-4; zbmp-2;

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