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bmi1a


Official Full Name
bmi1 polycomb ring finger oncogene 1a
Organism
Danio rerio
Gene ID
321505
Background
Predicted to enable promoter-specific chromatin binding activity. Acts upstream of or within cerebellum development; hematopoietic stem cell migration; and primitive hemopoiesis. Predicted to be located in nucleus. Predicted to be part of PRC1 complex. Is expressed in eye; gonad; and midbrain hindbrain boundary. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; hepatocellular carcinoma; and renal Wilms' tumor. Orthologous to several human genes including BMI1 (BMI1 proto-oncogene, polycomb ring finger). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
bmi1; psc1; pcgf4; wu:fb17g03; wu:fd18f06

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