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BCDIN3D


Official Full Name
BCDIN3 domain containing RNA methyltransferase
Organism
Homo sapiens
Gene ID
144233
Background
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
Synonyms
SPMIP7; C7orf72; SPATA48

Cat.No. Product Name Price
SHH245786 shRNA set against Human BCDIN3D (NM_181708.2) Inquiry
SHH245790 shRNA set against Mouse BCDIN3D (NM_029236.2) Inquiry
SHH245794 shRNA set against Rat BCDIN3D (NM_001108751.1) Inquiry
Cat.No. Product Name Price
CDFR008338 Rat Bcdin3d cDNA Clone(NM_001108751.1) Inquiry
MiUTR1M-00691 BCDIN3D miRNA 3'UTR clone Inquiry
MiUTR3H-13711 BCDIN3D miRNA 3'UTR clone Inquiry
CDCB157824 Human BCDIN3D ORF clone (BC053560) Inquiry
CDCB194520 Rabbit BCDIN3D ORF clone (XM_008256429.1) Inquiry
CDCR375381 Rat Bcdin3d ORF Clone(NM_001108751.1) Inquiry
CDCS417652 Human BCDIN3D ORF Clone (BC053560) Inquiry
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