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BC060632

Official Full Name
MTSS I-BAR domain containing 2
Organism
Mus musculus
GeneID
244654
Background
Enables actin monomer binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and small GTPase binding activity. Acts upstream of or within lamellipodium organization and membrane organization. Located in several cellular components, including cortical actin cytoskeleton; lamellipodium; and ruffle. Is expressed in several structures, including central nervous system; gut; musculoskeletal system; otic capsule; and vibrissa. Human ortholog(s) of this gene implicated in intellectual developmental disorder with ocular anomalies and distinctive facial features. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ABBA; Mtss1l;

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