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BBS7


Official Full Name
Bardet-Biedl syndrome 7
Organism
Homo sapiens
Gene ID
55212
Background
This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014]
Synonyms
BBS2L1

Cat.No. Product Name Price
SHG092149 shRNA set against Rat Bbs7(NM_001012180.1) Inquiry
SHH245178 shRNA set against Human BBS7 (NM_176824.2) Inquiry
SHH245182 shRNA set against Mouse BBS7 (NM_027810.3) Inquiry
SHH245186 shRNA set against Rat BBS7 (NM_001012180.1) Inquiry
SHW010492 shRNA set against Danio rerio BBS7 (NM_001077145) Inquiry
Cat.No. Product Name Price
CDFR002605 Rat Bbs7 cDNA Clone(NM_001012180.1) Inquiry
MiUTR1R-00520 BBS7 miRNA 3'UTR clone Inquiry
MiUTR3H-09334 BBS7 miRNA 3'UTR clone Inquiry
MiUTR3H-09335 BBS7 miRNA 3'UTR clone Inquiry
CDCB171967 Danio rerio BBS7 ORF Clone (NM_001077145) Inquiry
CDCB184241 Rabbit BBS7 ORF clone (XM_008267915.1) Inquiry
CDCL182820 Mouse BBS7 ORF clone(NM_027810.3) Inquiry
CDCR369693 Rat Bbs7 ORF Clone(NM_001012180.1) Inquiry
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