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BBS4


Official Full Name
Bardet-Biedl syndrome 4
Organism
Homo sapiens
Gene ID
585
Background
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Cat.No. Product Name Price
SHH245154 shRNA set against Human BBS4 (NM_033028.4) Inquiry
SHH245158 shRNA set against Mouse BBS4 (NM_175325.3) Inquiry
SHH245162 shRNA set against Rat BBS4 (NM_001106826.1) Inquiry
SHW003799 shRNA set against Chicken BBS4 (NM_001277458) Inquiry
SHW010626 shRNA set against Danio rerio BBS4 (NM_001077466) Inquiry
Cat.No. Product Name Price
CDFR006553 Rat Bbs4 cDNA Clone(NM_001106826.1) Inquiry
MiUTR3H-03317 BBS4 miRNA 3'UTR clone Inquiry
CDCB165274 Chicken BBS4 ORF Clone (NM_001277458) Inquiry
CDCB172101 Danio rerio BBS4 ORF Clone (NM_001077466) Inquiry
CDCB189442 Rabbit BBS4 ORF clone (XM_002722627.2) Inquiry
CDCL182818 Mouse BBS4 ORF clone(NM_175325.3) Inquiry
CDCR373564 Rat Bbs4 ORF Clone(NM_001106826.1) Inquiry
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