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B3GALT4


Official Full Name
beta-1,3-galactosyltransferase 4
Organism
Homo sapiens
Gene ID
8705
Background
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
Synonyms
GALT2; GALT4; BETA3GALT4

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SHG088453 shRNA set against Human B3GALT4(NM_003782.3) Inquiry
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Cat.No. Product Name Price
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MiUTR1M-01931 B3GALT4 miRNA 3'UTR clone Inquiry
CDCB158578 Human B3GALT4 ORF clone (BC032574) Inquiry
CDCB185575 Rabbit B3GALT4 ORF clone (XM_002714617.2) Inquiry
CDCR253788 Mouse B3galt4 ORF Clone(NM_019420.2) Inquiry
CDCR286465 Human B3GALT4 ORF Clone(NM_003782.3) Inquiry
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