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ARNTL2


Official Full Name
basic helix-loop-helix ARNT like 2
Organism
Homo sapiens
Gene ID
56938
Background
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Synonyms
BMAL2; CLIF; MOP9; PASD9; ARNTL2; bHLHe6

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Cat.No. Product Name Price
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CDCB184711 Rabbit ARNTL2 ORF clone (XM_008259488.1) Inquiry
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CDCR030370 Mouse Arntl2 ORF clone (NM_172309.1) Inquiry
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