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Apobec3

Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
Organism
Mus musculus
GeneID
80287
Background
Predicted to enable several functions, including cytidine deaminase activity; identical protein binding activity; and zinc ion binding activity. Involved in negative regulation of viral genome replication and transposable element silencing. Acts upstream of or within hematopoietic progenitor cell differentiation; regulation of defense response to virus; and regulation of viral life cycle. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to several human genes including APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B); APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D); and APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Apobec3; Arp3; Rfv3; Cem15; Apobec; Gm20117;

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