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AP3B2


Official Full Name
adaptor related protein complex 3 subunit beta 2
Organism
Homo sapiens
Gene ID
8120
Background
Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]
Synonyms
DEE48; NAPTB; EIEE48

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SHH237894 shRNA set against Mouse AP3B2 (NM_021492.3) Inquiry
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CDCR288531 Human AP3B2 ORF Clone(NM_004644.3) Inquiry
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