Official Full Name

angiopoietin-like 3

Background

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]

Synonyms

ANGPTL3; angiopoietin-like 3; ANL3; ANG-5; FHBL2; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; angiopoietin-like protein 3; fb60e11; fb66h02; wu:fb60e11; wu:fb66h02; zgc:111943