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Akr1C18


Official Full Name
aldo-keto reductase family 1, member C18
Organism
Mus musculus
Gene ID
105349
Background
Enables 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity. Acts upstream of or within parturition and progesterone catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; female reproductive system; and lung. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to human AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Akr1c18

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