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Akr1A4

Official Full Name
aldo-keto reductase family 1, member A1
Organism
Mus musculus
GeneID
58810
Background
Enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in D-glucuronate catabolic process to D-xylulose 5-phosphate and cellular detoxification of aldehyde. Acts upstream of or within D-glucuronate catabolic process; L-ascorbic acid biosynthetic process; and aldehyde catabolic process. Located in apical plasma membrane. Is active in cytosol and synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Akr1a1; Akr1a4; 2610201A18Rik;

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