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AKAP5


Official Full Name
A-kinase anchoring protein 5
Organism
Homo sapiens
Gene ID
9495
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]
Synonyms
H21; AKAP75; AKAP79

Cat.No. Product Name Price
SHH234286 shRNA set against Human AKAP5 (NM_004857.3) Inquiry
SHH234290 shRNA set against Mouse AKAP5 (NM_001101471.1) Inquiry
SHH234294 shRNA set against Rat AKAP5 (NM_133515.2) Inquiry
Cat.No. Product Name Price
MiUTR1H-00271 AKAP5 miRNA 3'UTR clone Inquiry
CDCR026298 Mouse Akap5 ORF clone (NM_001101471.1) Inquiry
CDCB189291 Rabbit AKAP5 ORF clone (XM_008271886.1) Inquiry
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