Pages
Products

AIFM1


Official Full Name
apoptosis inducing factor mitochondria associated 1
Organism
Homo sapiens
Gene ID
9131
Background
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Synonyms
AIF; AUNX1; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6; SEMDHL

Cat.No. Product Name Price
SHG048403 shRNA set against Mouse Aifm1(NM_012019.2) Inquiry
SHH233918 shRNA set against Human AIFM1 (NM_004208.3) Inquiry
SHH233922 shRNA set against Mouse AIFM1 (NM_012019.2) Inquiry
SHH233926 shRNA set against Rat AIFM1 (NM_031356.1) Inquiry
SHW000687 shRNA set against Chicken AIFM1 (NM_001007490) Inquiry
SHW016340 shRNA set against Danio rerio AIFM1 (NM_200102) Inquiry
Cat.No. Product Name Price
CDFR012661 Rat Aifm1 cDNA Clone(NM_031356.1) Inquiry
MiUTR1M-01343 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR1R-05702 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR3H-02613 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR3H-02614 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR3H-02615 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR3H-02616 AIFM1 miRNA 3'UTR clone Inquiry
MiUTR3H-02617 AIFM1 miRNA 3'UTR clone Inquiry
SKO0295 AIFM1 Validated sgRNA vector Inquiry
CDCB162162 Chicken AIFM1 ORF Clone (NM_001007490) Inquiry
CDCB177815 Danio rerio AIFM1 ORF Clone (NM_200102) Inquiry
CDCB189147 Rabbit AIFM1 ORF clone (XM_002720290.2) Inquiry
CDCR026024 Mouse Aifm1 ORF clone (NM_012019.2) Inquiry
CDCR349672 Human AIFM1 ORF Clone(NM_001130846.2) Inquiry
CDCR379694 Rat Aifm1 ORF Clone(NM_031356.1) Inquiry
CDCS407955 Human AIFM1 ORF Clone (BC139738) Inquiry
Quick Inquiry