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ACTL6B


Official Full Name
actin like 6B
Organism
Homo sapiens
Gene ID
51412
Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Synonyms
IMD43; AMYLD6; MHC1D4

Cat.No. Product Name Price
AD00598Z Human ACTL6B adenoviral particles Inquiry
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SHG036493 shRNA set against Mouse Actl6b(NM_031404.4) Inquiry
SHH230974 shRNA set against Human ACTL6B (NM_016188.4) Inquiry
SHH230978 shRNA set against Mouse ACTL6B (NM_031404.4) Inquiry
SHH230982 shRNA set against Rat ACTL6B (NM_001105917.1) Inquiry
SHW008769 shRNA set against Danio rerio ACTL6B (NM_001020740) Inquiry
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CDFR005644 Rat Actl6b cDNA Clone(NM_001105917.1) Inquiry
MiUTR1M-01146 ACTL6B miRNA 3'UTR clone Inquiry
MiUTR3H-12452 ACTL6B miRNA 3'UTR clone Inquiry
CDCB170244 Danio rerio ACTL6B ORF Clone (NM_001020740) Inquiry
CDCB183691 Rabbit ACTL6B ORF clone (XM_002711912.2) Inquiry
CDCR372723 Rat Actl6b ORF Clone(NM_001105917.1) Inquiry
CDCS414203 Human ACTL6B ORF Clone (BC020944) Inquiry
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