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ABCG8


Official Full Name
ATP binding cassette subfamily G member 8
Organism
Homo sapiens
Gene ID
64241
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
Synonyms
ATP6B

Cat.No. Product Name Price
AD00475Z Human ABCG8 adenoviral particles Inquiry
Cat.No. Product Name Price
SHG025459 shRNA set against Rat Abcg8(NM_130414.2) Inquiry
SHG025399 shRNA set against Human ABCG8(NM_022437.2) Inquiry
SHG025477 shRNA set against Mouse Abcg8(NM_026180.2) Inquiry
SHH229362 shRNA set against Human ABCG8 (NM_022437.2) Inquiry
SHH229366 shRNA set against Mouse ABCG8 (NM_026180.2) Inquiry
SHH229370 shRNA set against Rat ABCG8 (NM_130414.2) Inquiry
SHW012325 shRNA set against Danio rerio ABCG8 (NM_001114569) Inquiry
Cat.No. Product Name Price
CDFG003730 Human ABCG8 cDNA Clone(NM_022437.2) Inquiry
CDFR013889 Rat Abcg8 cDNA Clone(NM_130414.2) Inquiry
MiUTR1H-00061 ABCG8 miRNA 3'UTR clone Inquiry
MiUTR1M-01061 ABCG8 miRNA 3'UTR clone Inquiry
MiUTR1R-00040 ABCG8 miRNA 3'UTR clone Inquiry
CDCB173800 Danio rerio ABCG8 ORF Clone (NM_001114569) Inquiry
CDCB187565 Rabbit ABCG8 ORF clone (XM_002709736.2) Inquiry
CDCR023086 Mouse Abcg8 ORF clone (NM_026180.2) Inquiry
CDCR307816 Human ABCG8 ORF Clone(NM_022437.2) Inquiry
CDCR380923 Rat Abcg8 ORF Clone(NM_130414.2) Inquiry
CDCS415496 Human ABCG8 ORF Clone (BC113657) Inquiry
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