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ABCD2


Official Full Name
ATP binding cassette subfamily D member 2
Organism
Homo sapiens
Gene ID
225
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]
Synonyms
AMOG

Cat.No. Product Name Price
SHG150611 shRNA set against Rat Ccl17(NM_057151.1) Inquiry
SHG024641 shRNA set against Mouse Abcd2(NM_011994.2) Inquiry
SHG024659 shRNA set against Human ABCD2(NM_005164.3) Inquiry
SHG024695 shRNA set against Rat Abcd2(NM_033352.1) Inquiry
SHG150557 shRNA set against Human CCL17(NM_002987.2) Inquiry
SHH229210 shRNA set against Human ABCD2 (NM_005164.3) Inquiry
SHH229214 shRNA set against Mouse ABCD2 (NM_011994.2) Inquiry
SHH229218 shRNA set against Rat ABCD2 (NM_033352.1) Inquiry
SHH257521 shRNA set against Human CCL17 (NM_002987.2) Inquiry
SHH257525 shRNA set against Mouse CCL17 (NM_011332.3) Inquiry
SHH257529 shRNA set against Rat CCL17 (NM_057151.1) Inquiry
SHW003216 shRNA set against Chicken ABCD2 (NM_001199395) Inquiry
SHW004525 shRNA set against Chicken CCL17 (NM_001293309) Inquiry
Cat.No. Product Name Price
MiUTR1R-00789 CCL17 miRNA 3'UTR clone Inquiry
MiUTR1M-01051 ABCD2 miRNA 3'UTR clone Inquiry
MiUTR1H-01793 CCL17 miRNA 3'UTR clone Inquiry
MiUTR1H-00046 ABCD2 miRNA 3'UTR clone Inquiry
CDFR013757 Rat Ccl17 cDNA Clone(NM_057151.1) Inquiry
CDCB190813 Rabbit ABCD2 ORF clone (XM_008259406.1) Inquiry
CDFR013017 Rat Abcd2 cDNA Clone(NM_033352.1) Inquiry
CDFH002933 Human CCL17 cDNA Clone(NM_002987.2) Inquiry
MiUTR1R-00033 ABCD2 miRNA 3'UTR clone Inquiry
CDCR380790 Rat Ccl17 ORF Clone(NM_057151.1) Inquiry
CDCR380064 Rat Abcd2 ORF Clone(NM_033352.1) Inquiry
CDCR023000 Mouse Abcd2 ORF clone (NM_011994.2) Inquiry
CDCL183085 Human CCL17 ORF clone(NM_002987.2) Inquiry
CDCB181710 Rabbit CCL17 ORF clone (XM_008257335.1) Inquiry
CDCB166000 Chicken CCL17 ORF Clone (NM_001293309) Inquiry
CDCB164691 Chicken ABCD2 ORF Clone (NM_001199395) Inquiry
CDCB157329 Mouse CCL17 ORF clone (NM_011332.2) Inquiry
CDCR043320 Mouse Ccl17 ORF clone (NM_011332.3) Inquiry
CDCB156571 Cynomolgus CCL17 ORF clone Inquiry
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