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ABCC5


Official Full Name
ATP binding cassette subfamily C member 5
Organism
Homo sapiens
Gene ID
10057
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Synonyms
cb706; fj35g11; atp[a]3A; wu:fj35g11; wu:fq14g09

Cat.No. Product Name Price
AD00459Z Human ABCC5 adenoviral particles Inquiry
Cat.No. Product Name Price
SHG023983 shRNA set against Rat Abcc5(NM_053924.1) Inquiry
SHG024193 shRNA set against Mouse Abcc5(NM_176839.1) Inquiry
SHG024211 shRNA set against Human ABCC5(NM_005688.2) Inquiry
SHG024247 shRNA set against Human ABCC5(NM_001023587.1) Inquiry
SHG024319 shRNA set against Mouse Abcc5(NM_013790.2) Inquiry
SHH229150 shRNA set against Human ABCC5 (NM_005688.2) Inquiry
SHH229154 shRNA set against Mouse ABCC5 (NM_013790.2) Inquiry
SHH229158 shRNA set against Rat ABCC5 (NM_053924.1) Inquiry
SHW013695 shRNA set against Danio rerio ABCC5 (NM_001195613) Inquiry
Cat.No. Product Name Price
CDFH000056 Human ABCC5 cDNA Clone(NM_001023587.1) Inquiry
CDFH000057 Human ABCC5 cDNA Clone(NM_005688.2) Inquiry
CDFL000757 Mouse Abcc5 cDNA Clone(NM_176839.1) Inquiry
CDFR013636 Rat Abcc5 cDNA Clone(NM_053924.1) Inquiry
MiUTR1H-00042 ABCC5 miRNA 3'UTR clone Inquiry
MiUTR1M-01042 ABCC5 miRNA 3'UTR clone Inquiry
MiUTR1M-01043 ABCC5 miRNA 3'UTR clone Inquiry
MiUTR1R-00030 ABCC5 miRNA 3'UTR clone Inquiry
MiUTR3H-07516 ABCC5 miRNA 3'UTR clone Inquiry
CDCB175170 Danio rerio ABCC5 ORF Clone (NM_001195613) Inquiry
CDCB180624 Rabbit ABCC5 ORF clone (XM_002716488.2) Inquiry
CDCR022950 Human ABCC5 ORF clone (NM_001023587.1) Inquiry
CDCR022952 Human ABCC5 ORF clone (NM_005688.2) Inquiry
CDCR022958 Mouse Abcc5 ORF clone (NM_013790.2) Inquiry
CDCR022960 Mouse Abcc5 ORF clone (NM_176839.1) Inquiry
CDCR380509 Rat Abcc5 ORF Clone(NM_053924.1) Inquiry
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