Pages
Products

ASAH1


Official Full Name
N-acylsphingosine amidohydrolase 1
Organism
Homo sapiens
Gene ID
427
Background
This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]
Synonyms
AC; PHP; ASAH; PHP32; ACDase; SMAPME

Cat.No. Product Name Price
AD01404Z Human ASAH1 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH241058 shRNA set against Human ASAH1 (NM_004315.4) Inquiry
SHH241066 shRNA set against Rat ASAH1 (NM_053407.3) Inquiry
SHH241062 shRNA set against Mouse ASAH1 (NM_019734.2) Inquiry
SHW000535 shRNA set against Chicken ASAH1 (NM_001006453) Inquiry
Cat.No. Product Name Price
CDFH001251 Human ASAH1 cDNA Clone(NM_001127505.1) Inquiry
MiUTR1M-01724 ASAH1 miRNA 3'UTR clone Inquiry
MiUTR3H-12910 ASAH1 miRNA 3'UTR clone Inquiry
MiUTR3H-12911 ASAH1 miRNA 3'UTR clone Inquiry
MiUTR3H-12912 ASAH1 miRNA 3'UTR clone Inquiry
CDCB162010 Chicken ASAH1 ORF Clone (NM_001006453) Inquiry
CDCB194687 Rabbit ASAH1 ORF clone (XM_008250904.1) Inquiry
CDCR030644 Human ASAH1 ORF clone (NM_004315.4) Inquiry
CDCR030646 Human ASAH1 ORF clone (NM_001127505.1) Inquiry
CDCR030648 Human ASAH1 ORF clone (NM_177924.3) Inquiry
CDCR380239 Rat Asah1 ORF Clone(NM_053407.3) Inquiry
CDCS407808 Human ASAH1 ORF Clone (BC016828) Inquiry
CDCS407809 Human ASAH1 ORF Clone (BC016481) Inquiry
Quick Inquiry