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arxa


Official Full Name
aristaless related homeobox a
Organism
Danio rerio
Gene ID
30657
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within forebrain development; neuron development; and pancreatic A cell development. Predicted to be located in nucleus. Is expressed in several structures, including endocrine system; floor plate; forebrain; forebrain neural keel; and neural plate. Used to study epilepsy. Human ortholog(s) of this gene implicated in X-linked lissencephaly 2; X-linked recessive disease (multiple); corpus callosum agenesis-abnormal genitalia syndrome; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ARX (aristaless related homeobox). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
arx; phox2a

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