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ARHGAP4

Official Full Name
Rho GTPase activating protein 4
Background
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
ARHGAP4; Rho GTPase activating protein 4; rho GTPase-activating protein 4; ARHGAP 4; C1; KIAA0131; OTTHUMP00000026004; p115; RGC 1; RGC1; Rho GAP hematopoietic protein C1; Rho type GTPase activating protein 4; RhoGAP 4; RhoGAP4; OTTHUMP00000026003; OTTHUMP00000063090; OTTHUMP00000196209; OTTHUMP00000198723; Rho-GAP hematopoietic protein C1; rho-type GTPase-activating protein 4; SrGAP4

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