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ARHGAP11A


Official Full Name
Rho GTPase activating protein 11A
Organism
Homo sapiens
Gene ID
9824
Background
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]
Synonyms
GAP (1-12)

Cat.No. Product Name Price
SHW000560 shRNA set against Chicken ARHGAP11A (NM_001006479) Inquiry
SHW013673 shRNA set against Danio rerio ARHGAP11A (NM_001193539) Inquiry
SHW018389 shRNA set against Danio rerio ARHGAP11A (NM_213316) Inquiry
Cat.No. Product Name Price
CDCB159667 Human ARHGAP11A ORF clone (BC063444) Inquiry
CDCB162035 Chicken ARHGAP11A ORF Clone (NM_001006479) Inquiry
CDCB175148 Danio rerio ARHGAP11A ORF Clone (NM_001193539) Inquiry
CDCB179864 Danio rerio ARHGAP11A ORF Clone (NM_213316) Inquiry
CDCB192726 Rabbit ARHGAP11A ORF clone (XM_008269248.1) Inquiry
CDCS413777 Human ARHGAP11A ORF Clone (BC063444) Inquiry
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