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apoeb

Official Full Name
apolipoprotein Eb
Organism
Danio rerio
GeneID
30314
Background
Predicted to enable several functions, including cholesterol transfer activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Predicted to be involved in several processes, including cholesterol efflux; phospholipid efflux; and triglyceride-rich lipoprotein particle clearance. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of several cellular components, including chylomicron; low-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Predicted to be active in extracellular vesicle. Is expressed in several structures, including epidermis; fin bud; hematopoietic cell; median fin; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); artery disease (multiple); biliary tract cancer (multiple); eye disease (multiple); and familial hyperlipidemia (multiple). Orthologous to human APOE (apolipoprotein E). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
apoe; cb82; zeh1311; hm:zeh1311; wu:fa03d06; wu:fa97a11; wu:fc95h12; wu:fj54e06;

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