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APOBEC3H

Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
Background
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.
Synonyms
APOBEC3H; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H; DNA dC-> dU-editing enzyme APOBEC-3H; ARP10; APOBEC related protein 10; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3H; ARP 10; ARP-10; APOBEC-related protein 10; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H; DNA dC->dU-editing enzyme APOBEC-3H; DNA dC-> dU-editing enzyme APOBEC-3H

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