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Aph1c


Official Full Name
aph1 homolog C, gamma secretase subunit
Organism
Mus musculus
Gene ID
68318
Background
Predicted to enable endopeptidase activator activity and protein-macromolecule adaptor activity. Acts upstream of or within several processes, including chemical synaptic transmission; prepulse inhibition; and proteolysis. Part of gamma-secretase complex. Is expressed in brain and genitourinary system. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human APH1B (aph-1 homolog B, gamma-secretase subunit). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Gpr103b; C130060K24Rik

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