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ANKRD27

Official Full Name
ankyrin repeat domain 27
Organism
Homo sapiens
GeneID
84079
Background
Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endocytic recycling and negative regulation of SNARE complex assembly. Acts upstream of or within early endosome to late endosome transport. Located in several cellular components, including cytosol; endosome; and lysosome. Implicated in eosinophilic esophagitis. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
VARP; PP12899;

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