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ANKK1

Official Full Name
ankyrin repeat and kinase domain containing 1
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
Synonyms
ANKK1; ankyrin repeat and kinase domain containing 1; ankyrin repeat and protein kinase domain-containing protein 1; X kinase; sgK288; X-kinase; sugen kinase 288; protein kinase PKK2; PKK2

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