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ANK2


Official Full Name
ankyrin 2
Organism
Homo sapiens
Gene ID
287
Background
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
Synonyms
LQT4; ANK-2; FAP87; CFAP87; brank-2

Cat.No. Product Name Price
SHG058417 shRNA set against Mouse Ank2(NM_001034168.1) Inquiry
SHG058431 shRNA set against Mouse Ank2(NM_178655.3) Inquiry
SHG058525 shRNA set against Mouse Ank2(NM_001034168.1) Inquiry
SHG058529 shRNA set against Mouse Ank2(NM_178655.3) Inquiry
SHH226018 shRNA set against Mouse 2310030N02Rik (NM_001085493.1) Inquiry
SHH226022 shRNA set against Mouse 2310033E01Rik (NM_001037143.2) Inquiry
SHH236354 shRNA set against Human Ank2 (NM_001148.4) Inquiry
SHH236358 shRNA set against Mouse Ank2 (NM_178655.3) Inquiry
SHW007459 shRNA set against Danio rerio ANK2B (NM_001006063) Inquiry
Cat.No. Product Name Price
CDFG018066 Mouse Ank2 cDNA Clone(NM_001034168.1) Inquiry
CDFH000790 Human ANK2 cDNA Clone(NM_001127493.1) Inquiry
MiUTR1M-01466 ANK2 miRNA 3'UTR clone Inquiry
MiUTR1M-01467 ANK2 miRNA 3'UTR clone Inquiry
MiUTR4H-TG10562 ANK2 miRNA 3'UTR clone Inquiry
CDCB168934 Danio rerio ANK2B ORF Clone (NM_001006063) Inquiry
CDCB185409 Rabbit ANK2 ORF clone (XM_008267862.1) Inquiry
CDCR020294 Mouse 2310030N02Rik ORF clone (NM_001085493.1) Inquiry
CDCR020296 Mouse 2310033E01Rik ORF clone (NM_001037143.2) Inquiry
CDCR027574 Human ANK2 ORF clone (NM_001127493.1) Inquiry
CDCR027578 Mouse Ank2 ORF clone (NM_001034168.1) Inquiry
CDCR275012 Mouse Ank2 ORF Clone(NM_178655.3) Inquiry
CDCR353516 Human ANK2 ORF Clone(NM_001148.4) Inquiry
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