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alox5a

Official Full Name
arachidonate 5-lipoxygenase a
Organism
Danio rerio
GeneID
567204
Background
Enables arachidonate 5-lipoxygenase activity; arachidonate monooxygenase activity; and leukotriene-C4 synthase activity. Acts upstream of or within arachidonate metabolic process and inflammatory response to wounding. Predicted to be located in cytoplasm. Predicted to be active in nuclear envelope. Is expressed in pronephric duct. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
alox5; si:dkey-194n13.2;

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