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ALG2

Official Full Name
ALG2 alpha-1,3/1,6-mannosyltransferase
Organism
Homo sapiens
GeneID
85365
Background
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Synonyms
CDG1I; CDGIi; CMS14; NET38; CMSTA3; hALPG2;

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