Pages
Products

ALDH2


Official Full Name
aldehyde dehydrogenase 2 family member
Organism
Homo sapiens
Gene ID
217
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Synonyms
ALDM; ALDHI; ALDH-E2

Cat.No. Product Name Price
SHH234874 shRNA set against Mouse ALDH2 (NM_009656.3) Inquiry
SHG052597 shRNA set against Mouse Aldh2(NM_009656.3) Inquiry
SHG052633 shRNA set against Rat Aldh2(NM_032416.1) Inquiry
SHH225414 shRNA set against Mouse 1700058C13Rik (NM_028528.2) Inquiry
SHH225418 shRNA set against Mouse 1700061G19Rik (NM_030141.1) Inquiry
SHH234870 shRNA set against Human ALDH2 (NM_000690.3) Inquiry
SHH234878 shRNA set against Rat ALDH2 (NM_032416.1) Inquiry
SHW016673 shRNA set against Danio rerio ALDH2.1 (NM_200490) Inquiry
SHW018375 shRNA set against Danio rerio ALDH2.2 (NM_213301) Inquiry
Cat.No. Product Name Price
CDCR026604 Human ALDH2 ORF clone (NM_001204889.1) Inquiry
CDCS405837 Human ALDH2 ORF Clone (BC002967) Inquiry
CDFR012437 Rat Aldh2 cDNA Clone(NM_032416.1) Inquiry
MiUTR1M-00231 1700061G19RIK miRNA 3'UTR clone Inquiry
MiUTR1M-01395 ALDH2 miRNA 3'UTR clone Inquiry
MiUTR1R-00220 ALDH2 miRNA 3'UTR clone Inquiry
MiUTR3H-00002 ALDH2 miRNA 3'UTR clone Inquiry
CDCB160275 Human ALDH2 ORF clone (NM_000690) Inquiry
CDCB178148 Danio rerio ALDH2.1 ORF Clone (NM_200490) Inquiry
CDCB179850 Danio rerio ALDH2.2 ORF Clone (NM_213301) Inquiry
CDCB180920 Rabbit ALDH2 ORF clone (XM_008272245.1) Inquiry
CDCR019748 Mouse 1700058C13Rik ORF clone (NM_028528.2) Inquiry
CDCR019754 Mouse 1700061G19Rik ORF clone (NM_030141.1) Inquiry
CDCR380036 Rat Aldh2 ORF Clone(NM_032416.1) Inquiry
Quick Inquiry