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ALDH1L1

Official Full Name
aldehyde dehydrogenase 1 family, member L1
Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Synonyms
ALDH1L1; aldehyde dehydrogenase 1 family, member L1; formyltetrahydrofolate dehydrogenase , FTHFD; cytosolic 10-formyltetrahydrofolate dehydrogenase; 10 fTHF; cytosolic 10 formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolate dehydrogena; formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase; aldehyde dehydrogenase family 1 member L1; FDH; FTHFD; 10-fTHF; DKFZp781N0997

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