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ALDH1L1

Official Full Name
aldehyde dehydrogenase 1 family member L1
Organism
Homo sapiens
GeneID
10840
Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Synonyms
FDH; FTHFD; 10-fTHF; 10-FTHFDH;

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