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Akr1C14

Official Full Name
aldo-keto reductase family 1, member C14
Organism
Mus musculus
GeneID
105387
Background
Enables androsterone dehydrogenase activity. Predicted to be involved in glycoside metabolic process; prostaglandin metabolic process; and steroid metabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in gut; liver; metanephros; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Akr1c14; 9030611N15Rik;

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