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AJ237917


Official Full Name
FTO alpha-ketoglutarate dependent dioxygenase
Organism
Mus musculus
Gene ID
26383
Background
Enables broad specificity oxidative DNA demethylase activity and oxidative RNA demethylase activity. Involved in several processes, including DNA alkylation repair; RNA repair; and regulation of respiratory system process. Located in nucleus. Is expressed in several structures, including alimentary system; cerebral cortex; gonad; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic neuropathy; nuclear senile cataract; renal cell carcinoma (multiple); and type 2 diabetes mellitus. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
mKIAA1752

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