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AFF4

Official Full Name
ALF transcription elongation factor 4
Organism
Homo sapiens
GeneID
27125
Background
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]
Synonyms
MCEF; CHOPS; AF5Q31;

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