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ADCY5

Official Full Name
adenylate cyclase 5
Background
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Synonyms
ADCY5; adenylate cyclase 5; adenylate cyclase type 5; AC5; AC 5; ADCY 5; Adenylate cyclase type V; Adenylyl cyclase 5; ATP pyrophosphate lyase 5; OTTHUMP00000215640; OTTHUMP00000215641; OTTHUMP00000215642; OTTHUMP00000215643; ATP pyrophosphate-lyase 5; adenylyl cyclase type V; si:dkeyp-60a7.2; fan; fantasma; RUT

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