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ADAM18

Official Full Name
ADAM metallopeptidase domain 18
Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
ADAM18; ADAM metallopeptidase domain 18; a disintegrin and metalloproteinase domain 18; disintegrin and metalloproteinase domain-containing protein 18; putative ADAM18 gene product; ADAM27; tMDCIII; disintegrin and metalloproteinase domain-containing prot; ADAM 18; tMDC III; transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; MGC41836; MGC88272

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