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adam10a


Official Full Name
ADAM metallopeptidase domain 10a
Organism
Danio rerio
Gene ID
566044
Background
Predicted to enable metalloendopeptidase activity involved in amyloid precursor protein catabolic process. Predicted to be involved in Notch signaling pathway and membrane protein ectodomain proteolysis. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in synaptic membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
mKIAA0280; 2610030B18Rik; B930006L02Rik

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