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ACTL7B


Official Full Name
actin like 7B
Organism
Homo sapiens
Gene ID
10880
Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Synonyms
N4BP2; B3BP

Cat.No. Product Name Price
AD00600Z Human ACTL7B adenoviral particles Inquiry
Cat.No. Product Name Price
SHG036595 shRNA set against Rat Actl7b(NM_001025417.1) Inquiry
SHG036613 shRNA set against Mouse Actl7b(NM_025271.2) Inquiry
SHH230998 shRNA set against Human ACTL7B (NM_006686.3) Inquiry
SHH231002 shRNA set against Mouse ACTL7B (NM_025271.2) Inquiry
SHH231006 shRNA set against Rat ACTL7B (NM_001025417.1) Inquiry
Cat.No. Product Name Price
CDFR003968 Rat Actl7b cDNA Clone(NM_001025417.1) Inquiry
MiUTR1M-01148 ACTL7B miRNA 3'UTR clone Inquiry
MiUTR1R-00096 ACTL7B miRNA 3'UTR clone Inquiry
MiUTR4H-TG00118 ACTL7B miRNA 3'UTR clone Inquiry
CDCB186542 Rabbit ACTL7B ORF clone (XM_002708125.2) Inquiry
CDCL182556 Human ACTL7B ORF clone(NM_006686.3) Inquiry
CDCR256579 Mouse Actl7b ORF Clone(NM_025271.2) Inquiry
CDCR370945 Rat Actl7b ORF Clone(NM_001025417.1) Inquiry
CDCS412861 Human ACTL7B ORF Clone (BC033789) Inquiry
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