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AATK

Official Full Name
apoptosis associated tyrosine kinase
Organism
Homo sapiens
GeneID
9625
Background
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Synonyms
LMR1; AATYK; LMTK1; p35BP; AATYK1; PPP1R77;

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