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4931406I20RIK

Official Full Name
ring finger protein 220
Organism
Mus musculus
GeneID
66743
Background
Enables ubiquitin protein ligase activity. Involved in protein autoubiquitination and regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within nervous system development; positive regulation of DNA-binding transcription factor activity; and protein monoubiquitination. Located in cytoplasm. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; retina; and tooth. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 23. Orthologous to human RNF220 (ring finger protein 220). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
4732477A13; 4931406I20Rik; 5730503K05Rik;

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