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4921505C17RIK


Official Full Name
RPTOR independent companion of MTOR, complex 2
Organism
Mus musculus
Gene ID
78757
Background
Enables ribosome binding activity. Involved in several processes, including TORC2 signaling; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of protein phosphorylation. Acts upstream of or within several processes, including positive regulation of actin filament polymerization; regulation of establishment of cell polarity; and regulation of protein phosphorylation. Part of TORC2 complex. Is expressed in early conceptus; embryo; and oocyte. Human ortholog(s) of this gene implicated in breast ductal carcinoma; gastrointestinal system cancer (multiple); and lung cancer (multiple). Orthologous to human RICTOR (RPTOR independent companion of MTOR complex 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
A3F; KA6; ARP8; BK150C2.4.MRNA

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