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1810019J16RIK


Official Full Name
keratinocyte differentiation factor 1
Organism
Mus musculus
Gene ID
69073
Background
Involved in several processes, including positive regulation of epidermal cell differentiation; regulation of epidermal cell division; and skin epidermis development. Acts upstream of or within keratinocyte development and negative regulation of keratinocyte proliferation. Located in cell cortex; cell junction; and cell leading edge. Is expressed in several structures, including alimentary system; choroid plexus; lower urinary tract; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in ectodermal dysplasia 12. Orthologous to human KDF1 (keratinocyte differentiation factor 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Alox8; 8-LOX; 8S-LOX; Alox15b; 15-LOX-2; 15-LOX-B

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