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slc25a4

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Official Full Name
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Background
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
Synonyms
SLC25A4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; ANT1, PEO2, PEO3; ADP/ATP translocase 1; T1; ANT 1; ADP,ATP carrier protein 1; solute carrier family 25 member 4; heart/skeletal muscle ATP/ADP transloca; heart/skeletal muscle ATP/ADP translocator; ADP,ATP carrier protein, heart/skeletal muscle; adenine nucleotide translocator 1 (skeletal muscle); ANT; AAC1; ANT1; PEO2; PEO3; fa22e07; zgc:77591; wu:fa22e07; SLC25A5

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