Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and;renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the;sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses;the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane.;SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the;absorption of phosphate from the intestine (summary by Shibui et al., 1999 (PubMed 10319585)).
SLC17A4; solute carrier family 17 (sodium phosphate), member 4; putative small intestine sodium-dependent phosphate transport protein; KAIA2138; KIAA2138; MGC129623; Na/PO4 cotransporter; S17A4_HUMAN; SLC17A4 protein; Solute carrier family 17 (sodium phosphate) member 4; Solute carrier family 17 member 4; 9130214H05Rik